Journal
ORGANIC LETTERS
Volume 8, Issue 18, Pages 3995-3998Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol061461d
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Funding
- NIGMS NIH HHS [R01 GM028663-28, R01 GM028663-27, R01 GM028663, R01 GM028663-25, R01 GM028663-26, GM 28663] Funding Source: Medline
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A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl) aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.
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