4.4 Article

A novel silver iodide catalyzed Sonogashira coupling reaction

Journal

SYNLETT
Volume -, Issue 14, Pages 2261-2265

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-949640

Keywords

silver iodide; Sonogashira coupling reactions; terminal alkynes; aryl iodides; aryl bromides

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A novel and efficient Ag-catalyzed Sonogashira coupling reaction has been developed. Terminal alkynes couple with aryl iodides and aryl bromides in the presence of silver iodide, tripbenylphosphine and potassium carbonate to afford the corresponding cross-coupling products in high yields.

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