Journal
PHYSIOLOGICAL MEASUREMENT
Volume 27, Issue 9, Pages 839-850Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0967-3334/27/9/007
Keywords
bioelectrical impedance analysis; Cole model; four-frequency impedance measurement
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Conventional bioimpedance spectrometers measure resistance and reactance over a range of frequencies and, by application of a mathematical model for an equivalent circuit (the Cole model), estimate resistance at zero and infinite frequencies. Fitting of the experimental data to the model is accomplished by iterative, nonlinear curve fitting. An alternative fitting method is described that uses only the magnitude of the measured impedances at four selected frequencies. The two methods showed excellent agreement when compared using data obtained both from measurements of equivalent circuits and of humans. These results suggest that operational equivalence to a technically complex, frequency-scanning, phase-sensitive BIS analyser could be achieved from a simple four-frequency, impedance-only analyser.
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