4.6 Article

Tuberculosis: an under-diagnosed aetiological agent in uveitis with an effective treatment

Journal

EYE
Volume 20, Issue 9, Pages 1068-1073

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/sj.eye.6702093

Keywords

uveitis; tuberculosis; diagnosis; tuberculin test; antitubercular therapy

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Purpose To highlight the diversity of clinical presentations with tubercular uveitis in a nonendemic setting, and discuss the diagnostic approach and an effective treatment. Method Descriptive case series. Results A total of 12 cases of varied presentations of tubercular uveitis diagnosed over a period of 1 year of which six cases are described in detail. Presentations included choroidal tuberculomas, multifocal choroiditis, recurrent granulomatous uveitis, panuveitis with cystoid macular oedema, and serpiginous choroiditis. All cases had a chronic or recurrent course and responded very well to antitubercular treatment. Diagnosis was mainly assisted by positive tuberculin testing. Conclusion A high index of suspicion helps diagnose ocular tuberculosis in areas of low prevalence of the disease. It forms part of the differential diagnosis of any chronic or recurrent uveitis, especially in an at-risk patient. Antitubercular treatment seems highly effective.

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