Landmark-based registration of curves via the continuous wavelet transform

This article is concerned with the problem of the alignment of multiple sets of curves. We analyze two real examples arising from the biomedical area for which we need to test whether there are any statistically significant differences between two subsets of subjects. To synchronize a set of curves, we propose a new nonparametric landmark-based registration method based on the alignment of the structural intensity of the zero-crossings of a wavelet transform. The structural intensity is a recently proposed multiscale technique that highlights the main features of a signal observed with noise. We conduct a simulation study to compare our landmark-based registration approach with some existing methods for curve alignment. For the two real examples, we compare the registered curves with FANOVA techniques, and a detailed analysis of the warping functions is provided.