4.6 Article

Polycomb, pairing and PIWI - RNA silencing and nuclear interactions

Journal

TRENDS IN BIOCHEMICAL SCIENCES
Volume 31, Issue 9, Pages 485-487

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibs.2006.07.002

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In Drosophila, the RNA interference (RNAi) genes participate in Polycomb (Pc)-mediated transgene silencing. Recently, the involvement of the RNAi genes in Pc silencing, pairing-sensitive silencing and long-range contacts among Pc-associated sequences has been explored. These Pc-associated sequences are involved with the control of the proper expression of developmental HOX genes.

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