Flavone c-glycosides from Trollius ledebouri Reichb

A new acylated C-glycosylflavone ( 1) was isolated from Trollius ledebouri Reichb together with two known C-glycosyflavones ( 2, 3). The structures were elucidated by spectroscopic methods, including HRMS, IR, H-1 and C-13 NMR and 2D experiments (COSY, HMQC and HMBC). The anti-inflammatory activities of 1-3 were tested on TPA-induced mice ear edema (in vivo).