Journal
BRITISH JOURNAL OF HAEMATOLOGY
Volume 134, Issue 6, Pages 632-639Publisher
WILEY
DOI: 10.1111/j.1365-2141.2006.06243.x
Keywords
anticoagulation; patient self-management; cost; cost-effectiveness
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Demand for anticoagulation management is increasing due to an expansion of clinical indications for therapy. One possible model of care to meet demand is patient self-management (PSM), beneficial to patients who need control over their condition. This study aimed to determine the cost and cost-effectiveness of PSM of anticoagulation compared with routine clinic-based care for patients receiving long-term anticoagulation. A cost-utility analysis was conducted alongside a randomised controlled trial; 617 patients were recruited and followed up for 12 months. There was no significant difference in mean quality-adjusted life years (QALYs) between groups-after adjusting for baseline, the mean difference in QALYs was 0.009 (95% CI,) 0.012 to 0.030). Overall mean healthcare costs in the PSM arm were significantly higher at 417 pound (CI 394- pound 442) pound compared with 122 pound (CI 103- pound 144) pound in the control arm. Therefore, using a formal cost-effectiveness analysis, PSM of anticoagulation does not appear to be cost-effective. However, PSM may have other benefits in relieving pressure on traditional clinic-based care, and the cost-effectiveness of this model of care for some subgroups of anticoagulation patients needs to be explored further.
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