Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 16, Issue 17, Pages 4600-4602Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.06.009
Keywords
Rodgersia podophylla; rodgersinol; iNOS inhibitor; COX-2 inhibitor
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A novel compound, rodgersinol (1), was isolated from the aerial parts of Rodgersia podophylla and its structure was elucidated with various spectroscopic methods. Rodgersinol (1) exhibited the significant inhibitory effects on iNOS and COX-2 expressions in LPS-activated macrophages. (c) 2006 Elsevier Ltd. All rights reserved.
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