Journal
MEMORIAS DO INSTITUTO OSWALDO CRUZ
Volume 101, Issue 6, Pages 581-584Publisher
FUNDACO OSWALDO CRUZ
DOI: 10.1590/S0074-02762006000600001
Keywords
tuberculosis; epidemiology; drug resistance; South American Indians; genotyping
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This investigation aimed at the detection of Mycobacterium tuberculosis (MTB) in the sputum of Surui Indian subjects from Amazonia, Brazil. Polymerase chain reaction analyses were positive for 12 samples, five of which were also culture-positive (N = 147). Four MTB genotypes were identified, one of which showed resistance to rifampicin and isoniazid. The study also highlighted one village complex as of particular importance, considering the relatively high number of tuberculosis cases reported and of MTB isolates obtained.
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