Quantitative optical coherence tomographic elastography: method for assessing arterial mechanical properties

Optical coherence tomography elastography represents a potentially attractive new technique for measuring elastic properties of tissues on a micron scale. In this study, the feasibility of optical coherence tomography (OCT) to study the mechanical properties of phantoms and atherosclerotic arterial samples is reported. The elastic modulus of tissue-mimicking phantoms was measured using OCT and correlated with mechanical measurements. The results indicate that elastography based on OCT represents an attractive technique for evaluating the mechanical properties of tissues.