Journal
SYNLETT
Volume -, Issue 14, Pages 2246-2250Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-949623
Keywords
cellulose; copper; aza-Michael; amines; imidazoles; alpha,beta-unsaturated compounds; beta-amino compounds; N-substituted imidazoles
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Cellulose-supported copper(0) efficiently catalyzes the aza-Michael reaction of N-nucleophiles, such as amines and imidazoles with alpha,beta-unsaturated compounds to produce the corresponding beta-amino compounds and N-substituted imidazoles in excellent yields. The reactions are facile and the recovered catalyst is used for several cycles with consistent activity.
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