4.8 Article

Quantum dot encapsulation in viral capsids

Journal

NANO LETTERS
Volume 6, Issue 9, Pages 1993-1999

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/nl061165u

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Funding

  1. NIGMS NIH HHS [GM59249] Funding Source: Medline

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Incorporation of CdSe/ZnS semiconductor quantum dots ( QDs) into viral particles provides a new paradigm for the design of intracellular microscopic probes and vectors. Several strategies for the incorporation of QDs into viral capsids were explored; those functionalized with poly( ethylene glycol) ( PEG) can be self-assembled into viral particles with minimal release of photoreaction products and enhanced stability against prolonged irradiation.

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