Journal
ORGANIC LETTERS
Volume 8, Issue 19, Pages 4351-4354Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol061755z
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A two-step sequence involving an Ugi four-component reaction (Ugi-4CR) and a palladium-catalyzed intramolecular amidation of aryl iodide has been developed for rapid access to functionalized oxindole (1). Microwave heating was used to accelerate and to improve the efficiency of the intramolecular Buchwald-Hartwig reaction.
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