Before and after the spindle assembly checkpoint - An APC/C point of view

On May 17-21, 2006 the Cold Spring Harbor Laboratory meeting on the cell cycle reunited over 350 researchers to discuss new findings in the cell cycle field. A common thread that connected numerous presentations was the regulation of the anaphase promoting complex/cyclosome (APC/C). This was also the main theme of the lecture given by the keynote speaker, Marc Kirschner (Harvard), who talked about The unexpected importance of UbcH10 in both the G(1)/S transition and the initiation of anaphase, and it is also the main focus in this summary.