4.6 Article

Novel template-directed anodic phenol-coupling reaction

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 12, Issue 28, Pages 7482-7488

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200600375

Keywords

borates; C-C coupling; electrochemistry; oxidation; phenols

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Substituted phenols were anodically coupled to the corresponding 2,2'-biphenols via tetraphenoxy borate derivatives. This electrochemical method is particularly useful for methyl-substituted substrates, such as 2,4-dimethyl phenol. The selective ortho-coupling reaction can be easily performed on a multikilogram scale.

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