4.4 Article

ZrCl4 catalyzed highly selective and efficient Michael addition of heterocyclic enamines with α,β-unsaturated olefins

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 39, Pages 7001-7005

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.07.116

Keywords

zirconium tetrachloride; Michael addition; heterocyclic enamines; alpha,beta-unsaturated olefins

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Highly selective and efficient Michael additions of heterocyclic enamines, viz. indoles, pyrroles, and pyrazoles with alpha, beta-unsaturated olefins using 2 mol % of ZrC14 has been achieved. (c) 2006 Elsevier Ltd. All rights reserved.

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