Journal
ORGANIC LETTERS
Volume 8, Issue 20, Pages 4653-4655Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol061964j
Keywords
-
Categories
Ask authors/readers for more resources
4-Hhydroxyproline has been anchored to a polystyrene resin through click chemistry, and the resulting catalyst has been successfully applied to the direct aldol reaction in water. The high hydrophobicity of the resin and the presence of water are key to ensuring high stereoselectivity, whereas yield can be increased by using catalytic amounts of DiMePEG. This effect has been further demonstrated by the inefficiency of a homogeneous, more polar analogue.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available