Journal
ANNALS OF DERMATOLOGY
Volume 25, Issue 4, Pages 479-482Publisher
KOREAN DERMATOLOGICAL ASSOC
DOI: 10.5021/ad.2013.25.4.479
Keywords
Hepatitis C; Peginterferon alfa-2a; Psoriasis; Ribavirin
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A 56-year-old man with chronic hepatitis C was treated with pegylated interferon alfa-2a in combination with ribavirin. However, psoriatic lesions appeared and worsened dramatically during therapy. Because of the extensive skin eruptions, he stopped therapy for chronic hepatitis C and subsequently started narrow-band ultraviolet B phototherapy and topical calcipotriol/betamethasone dipropionate ointment. After this, the psoriasis improved in a slow but comprehensive manner. Our case suggests that physicians should keep in mind the possibility of psoriasis as a side effect of interferon treatment for chronic hepatitis C.
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