4.0 Article

New World Cutaneous Leishmaniasis Treated with Intralesional Injection of Pentavalent Antimony

Journal

ANNALS OF DERMATOLOGY
Volume 25, Issue 1, Pages 80-83

Publisher

KOREAN DERMATOLOGICAL ASSOC
DOI: 10.5021/ad.2013.25.1.80

Keywords

Cutaneous leishmaniasis; Leishmaniasis; Sodium stibogluconate (Pentostam (R))

Categories

Funding

  1. National Research Foundation of Korea (NRF)
  2. Korea government (MEST) [2011-0001390]
  3. NRF
  4. Ministry of Education, Science and Technology [2010-0002431]
  5. National Research Foundation of Korea [2010-0002431] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Cutaneous leishmaniasis is a skin infection caused by the Leishmania species, an intracellular protozoan parasite that is transmitted by various species of female sandflies. According to the geographic distribution and vectors, leishmaniasis is classified as Old World or New World cutaneous leishmaniasis. In Korea, 24 cases of Old World cutaneous leishmaniasis have been reported, but New World cutaneous leishmaniasis has not been reported as yet. A 37-year-old man presented with a 3-month history of a painful and erythematous nodule with two satellite papules on the left postauricular area and a papule on the left arm after traveling to the Amazon region in Brazil. After we performed skin biopsies of the lesions, diagnosis of cutaneous leishmaniasis was made by the histopathological findings. After intralesional injection of sodium stibogluconate (Pentostam (R), GlaxoSmithKline) twice a week for 4 weeks, the lesions improved with scarring. Herein, we discuss this case of New World cutaneous leishmaniasis that was successfully treated with intralesional injection of sodium stibogluconate (Pentostam (R)) in Korea. (Ann Dermatol 25(1) 80 similar to 83, 2013)

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