Journal
NATURE NEUROSCIENCE
Volume 9, Issue 10, Pages 1240-1242Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn1760
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Funding
- NEI NIH HHS [EY13788] Funding Source: Medline
- NIMH NIH HHS [MH-64024] Funding Source: Medline
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Neuronal responses to visual stimuli depend on both the nature of the stimulus and brain state. Here we examined the contrast sensitivity of visual thalamic neurons as awake rabbits shifted between alert and nonalert states. We found that despite a large increase in response gain with alertness, contrast sensitivity remained nearly constant. This accurate scaling might be achieved through a balanced increase in excitation and inhibition with alertness.
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