Journal
HUMAN REPRODUCTION
Volume 21, Issue 10, Pages 2606-2611Publisher
OXFORD UNIV PRESS
DOI: 10.1093/humrep/del234
Keywords
N2O; oxygen; pain relief; suction evacuation
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BACKGROUND: This prospective study assessed the role of a 50:50 mixture of nitrous oxide (N2O) and oxygen for pain relief during the termination of first trimester pregnancies by suction evacuation under conscious sedation. METHODS: Ninety women undergoing suction evacuation up to 12 weeks of gestation were randomized by a computer-generated randomization list and allocated using sealed envelopes to receive the N2O/O-2 mixture or air during the operation. Pain scores during and after suction evacuation, post-operative side effects and satisfaction level were compared. RESULTS: No statistically significant differences in pain scores, post-operative side effects and satisfaction levels were found between the two groups. CONCLUSION: N2O/O-2 did not reduce the pain level during suction evacuation for the first trimester pregnancy termination under conscious sedation.
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