Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 386, Issue 3, Pages 759-764Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-006-0469-3
Keywords
diffusion coefficient; nanospace; nano-particles; single-particle tracking; nanopillar chip
Ask authors/readers for more resources
Here we report an anomalous behavior of water, especially its viscosity and hydrodynamic flow, in a nanometer-confined space. As a typical model of a nanometer-confined space, the nanopillar chip, which was developed for DNA size-based separation was used, and single-particle tracking (SPT) technique was applied to investigate water viscosity and hydrodynamic flow in the nanopillar chip. The diffusion coefficients of nanospheres were almost one-third of the theoretical value derived from the Stokes-Einstein equation. This result gave indirect proof that water viscosity in a nanometer-confined space is higher than in a bulk solution. In order to improve resolution and throughput of the nanopillar chip for DNA separation, these potential factors affecting performance should be seriously considered.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available