Journal
JOURNAL OF APPLIED PHYSIOLOGY
Volume 101, Issue 4, Pages 1237-1242Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/japplphysiol.00500.2006
Keywords
physical activity; plasticity
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Funding
- NIA NIH HHS [R37 AG-25667, R01 AG-25032] Funding Source: Medline
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Exercise, cognition, and the aging brain. J Appl Physiol 101: 1237-1242, 2006. First published June 15, 2006; doi:10.1152/japplphysiol.000500.2006.-We provide a brief review of the literature on exercise effects on brain and cognition. To this end, we focus on both prospective and retrospective human epidemiological studies that have examined the influence of exercise and physical activity on cognition and dementia. We then examine the relatively small set of human randomized clinical trials that have, for the most part, focused on exercise training effects on cognition. Next, we discuss animal research that has examined the molecular, cellular, and behavioral effects of exercise training. Finally, we conclude with a summary and brief discussion of important future directions of research on fitness cognition and brain.
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