4.5 Article

Selectivity in DNA interstrand-stacking

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 16, Issue 19, Pages 5062-5065

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.07.039

Keywords

oligonucleotide; mimic; excimer; stacking; exciplex

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The synthesis and spectroscopic investigation of DNA hybrids containing non-nucleosidic pyrene and phenanthrene building blocks is reported. It was found that interstrand-stacking of the polyaromatic compounds in the DNA duplex takes place with a high degree of selectivity. (c) 2006 Elsevier Ltd. All rights reserved.

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