Journal
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
Volume 25, Issue 10, Pages 2639-2644Publisher
WILEY
DOI: 10.1897/06-142R.1
Keywords
hydrophobic organic chemicals; effective chemical activity; toxicity cutoff; baseline toxicity; quantitative structure-activity relationships
Categories
Ask authors/readers for more resources
Effect concentrations for aquatic baseline toxicity generally decrease with increasing log octanol-water partition coefficient (K-ow) values of up to 5 to 6, whereas less is known about the baseline toxicity of organic chemicals with log K-ow values above 6. A physicochemical analysis of the dissolution process for organic chemicals was combined with reported baseline toxicity data, leading to the following conclusions. First, no absolute hydrophobicity cutoff exists for baseline toxicity at a log K-ow value of 6, because aquatic baseline toxicity for fish and algae was observed for chemicals with log K-ow values greater than 6.5 and with effect concentrations less than 10 mu g/L. Second, the baseline toxicity of hydrophobic organic substances was exerted at a relatively constant chemical activity of 0.01 to 0.1. Finally, organic chemicals with high melting points cannot provide sufficient chemical activity to exert baseline toxicity when considered as individual, pure chemicals. However, such substances are still expected to contribute to baseline toxicity when part of a complex mixture.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available