Journal
CURRENT OPINION IN PHARMACOLOGY
Volume 6, Issue 5, Pages 522-527Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coph.2006.05.004
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Dendrimers represent a class of polymers characterised by their well-defined structure, with a high degree of molecular uniformity and low polydispersity. They have found a wide-range of pharmaceutical applications; however, more recently, they have been shown to function as effective intracellular carriers for drugs. In addition, dendrimers have been shown to be capable of bypassing efflux transporters. A new generation of dendrimer-based delivery systems will enable the efficient transport of drugs across cellular barriers.
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