4.5 Review

Human beta-defensin-3: A promising antimicrobial peptide

Journal

MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 6, Issue 10, Pages 1063-1073

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955706778560193

Keywords

antimicrobial peptides; human beta-defensin-3; drug resistant microorganisms; new antimicrobial drugs; peptide structure

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The field of naturally occurring antimicrobial peptides is a research area rapidly expanding due to the high potential of such molecules as new antimicrobial drugs. In this regard, the human beta-defensin-3 is particularly attractive because of its strong antibacterial activity, relative salt-insensitiveness and low toxicity for host cells.

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