Journal
PHYSIOLOGY
Volume 21, Issue -, Pages 362-369Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00024.2006
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Signaling through mammalian target of rapamycin (mTOR) is activated by amino acids, insulin, and growth factors, and impaired by nutrient or energy deficiency. mTOR plays key roles in cell physiology, mTOR regulates numerous components involved in protein synthesis, including initiation and elongation factors, and the biogenesis of ribosomes themselves.
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