Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 16, Issue 19, Pages 5001-5004Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.07.056
Keywords
NR2E3; PNR; RNR; age-related macular degeneration; AMD; nuclear receptor; ophthalmics
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Agonists of NR2E3 (PNR, RNR) have been identified and optimized to EC50 < 200 nM. A tritiated analogue of one agonist was prepared to aid in the development of a binding assay. (c) 2006 Elsevier Ltd. All rights reserved.
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