Journal
ORGANIC LETTERS
Volume 8, Issue 21, Pages 4755-4758Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0618353
Keywords
-
Categories
Ask authors/readers for more resources
Intramolecular hydroamination of cyclohexa-2,5-dienes led with high selectivity to the corresponding bicyclic allylic amines. This study demonstrates that the reaction does not proceed through a direct hydroamination of one of the diastereotopic olefins but more likely involves a diastereoselective protonation of a pentadienyl anion, followed by addition of a lithium amide across the double bond of the resulting 1,3-diene, and is concluded by a highly regioselective protonation of the final allylic anion.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available