Journal
YEAST
Volume 23, Issue 13, Pages 913-919Publisher
WILEY
DOI: 10.1002/yea.1420
Keywords
gene ontology; Schizosaccharomyces. pombe; annotation; curation; reference genome; fission yeast
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In this review, we present an overview of the Gene Ontology (GO) structure and describe how the GO is implemented for Sz. pombe and made available via Sz. pombe GeneDB (http://www.genedb.org/genedb/pombe/). We give a detailed progress report of Sz. pombe GO annotation, providing the current status of both manual and automatic annotations. Fission yeast has at least one GO annotation for 98.3% of its genes (excluding annotations to 'unknown' terms), greater than the current percentage coverage for any other organism. Approximately 65% (3225 gene products) have at least one annotation to each of the three ontologies (biological process, cellular component and molecular function). Approximately 30% (1443 gene products) have GO terms derived directly from small-scale experiments in fission yeast, supporting the validity of fission yeast as a model eukaryote and a reference organism. Copyright (c) 2006 John Wiley & Sons, Ltd.
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