Journal
BEHAVIOURAL BRAIN RESEARCH
Volume 173, Issue 2, Pages 320-325Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bbr.2006.06.035
Keywords
aging; amygdala; anxiety; BLAST; stereology
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Aging is associated with behavioral changes, including increased anxiety. In this study we confirmed a hyperanxious status in aged animals, measured in the elevated-plus maze and in the acoustic startle. Subsequently, we searched for age-related changes in the volume and cell numbers in the amygdala or in the bed nucleus of the stria terminalis, but failed to detect gross structural changes in these two brain areas, both implicated in emotionality. (c) 2006 Elsevier B.V. All rights reserved.
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