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A short and efficient synthesis of (R)-(-)-sporochnol A

Journal

TETRAHEDRON-ASYMMETRY
Volume 17, Issue 18, Pages 2632-2636

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2006.09.013

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A short and efficient synthesis of (R)-(-)-sporochnol A in five steps and 9% overall yield has been developed. The sequence uses as starting material the easily available enantiopure monoketal derived from 1,4-cyclohexanedione and (R,R)-hydrobenzoin that serves as a chiral auxiliary. (c) 2006 Elsevier Ltd. All rights reserved.

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