4.4 Article

Synthetic studies on the MARDi cascade: Stereoselective preparation of sulfonyl-substituted seven-membered rings

Journal

SYNLETT
Volume -, Issue 17, Pages 2751-2754

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-950261

Keywords

stereoselective synthesis; domino reactions; multicomponent reactions; ring expansion; cycloheptane

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A stercoselective synthesis of functionalized sulfonyl-substituted cycloheptanes is described. The approach involves a formal two-carbon ring expansion of 2-benzenesuffortyl cyclopentanones through a base-induced anionic domino three-component transformation named the MARDi cascade.

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