Journal
NATURE
Volume 443, Issue 7113, Pages 796-802Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nature05293
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Funding
- NIA NIH HHS [R01 AG012282] Funding Source: Medline
- NINDS NIH HHS [R01 NS033376] Funding Source: Medline
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Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease trigger neuronal cell death through endogenous suicide pathways. Surprisingly, although the cell death itself may occur relatively late in the course of the degenerative process, the mediators of the underlying cell-death pathways have shown promise as potential therapeutic targets.
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