4.4 Article

Phenylsilane as an active amidation reagent for the preparation of carboxamides and peptides

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 43, Pages 7649-7651

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.08.024

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The use of phenylsilane as a mild coupling reagent for amidation reactions is reported. Applicability to both solution- and solid-phase chemistry has been demonstrated for a variety of arnines and carboxylic acids. (c) 2006 Published by Elsevier Ltd.

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