Journal
STATISTICS IN MEDICINE
Volume 25, Issue 20, Pages 3430-3442Publisher
JOHN WILEY & SONS LTD
DOI: 10.1002/sim.2706
Keywords
baselines; bioequivalence; binary data; carry-over; survival analysis
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Papers on cross-over trials that have appeared in the first 25 years of Statistics in Medicine are reviewed. Papers on bioequivalence are also considered. After a brief statistical summary, individual papers are discussed under seven headings: 1. The two-stage analysis of AB/BA trials, 2. Baselines, 3. Binary and categorical data, 4. Survival data, 5. Modelling carry-over, 6. Bioequivalence and 7. Components of variation. Finally, a brief assessment of the importance in this field of Statistics in Medicine is given. Copyright (c) 2006 John Wiley & Sons, Ltd.
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