Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 386, Issue 6, Pages 1689-1693Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-006-0740-7
Keywords
titanocene dichloride; ICP-AES; transferrin; antitumor
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We report a simple method that combines dialysis, as a purification method, with the multielement capability of ICP to determine the titanium-to-transferrin mole ratio at physiological pH, under buffer conditions. The method, by means of which titanium and transferrin are determined simultaneously, enabled us to assess the binding capacities of different titanocene complexes.
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