Journal
REPRODUCTIVE BIOMEDICINE ONLINE
Volume 13, Issue 5, Pages 661-667Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1472-6483(10)60656-6
Keywords
clinical pregnancy; ICSI; implantation rate; meiotic spindle; oocyte morphology
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With a view to correlating oocyte morphology and meiotic spindle presence to clinical intracytoplasmic sperm injection (ICSI) outcomes, 967 oocytes that led to 967 transferred embryos in 404 embryo transfers were studied. No relationship was found between oocyte morphology (ooplasm texture, perivitelline space largeness, perivitelline space granulation absence/presence and the first polar body shape) or meiotic spindle presence or absence and clinical pregnancy per transfer and implantation rates after ICSI. It was concluded that oocyte morphology and meiotic spindle presence or absence can only predict fertilization, cleavage rates and embryo quality, as previously described in the literature, but do not help in daily ICSI practice in the choice of the metaphase II oocyte that will lead to the embryo that starts clinical pregnancy.
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