Journal
ARCHIVES OF NEUROLOGY
Volume 63, Issue 11, Pages 1602-1604Publisher
AMER MEDICAL ASSOC
DOI: 10.1001/archneur.63.11.1602
Keywords
-
Categories
Ask authors/readers for more resources
Objective: To assess the effect of repetitive transcranial magnetic stimulation (rTMS) to the dorsolateral prefrontal cortex (DLPFC) on picture naming in patients with Alzheimer disease (AD). Design: Experimental study. Patients with AD under went rTMS in real and control conditions during picture naming tasks. Setting: San Giovanni di Dio Fatebenefratelli Scientific Institute in Brescia, Italy. Patients: Fifteen patients with probable AD. Intervention: High-frequency rTMS was applied to the left and right DLPFC during object and action naming. Main Outcome Measures: Language ability was assessed by accuracy of verbal response during online rTMS. Results: Stimulation to the left and right DLPFC improved accuracy in action naming. Conclusions: These findings indicate that rTMS to the DLPFC, which speeds up action naming in normal controls, improves performance in patients with AD. While the mechanisms of rTMS-induced naming facilitation in these patients are unknown, the procedure may be worth testing as a novel approach to the treatment of language dysfunction.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available