Journal
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Volume 19, Issue 11, Pages 1326-1331Publisher
MOSBY, INC
DOI: 10.1016/j.echo.2006.05.024
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Systole (S) and diastole (D) are fundamental to cardiac function, yet their durations are not routinely evaluated. We defined the S/D duration ratio in 11 children with restrictive cardiomyopathy (CM) and 31 control subjects, using tricuspid regurgitant now duration. We correlated S/D ratio, S duration, and D duration with heart rate and compared groups. Heart rates of control subjects and patients with restrictive CM were similar (P =.995). The S/D ratio was higher in patients with restrictive CM than in control subjects (1.6 +/- 0.81 vs 0.8 +/- 0.19, P <.001) as a result of shortened D (0.43 +/- 0.13 vs 0.56 +/- 0.06, P <.01) and prolonged S (0.58 +/- 0.12 vs 0.44 +/- 0.06, P <.01). The S/D ratio was highly correlated to heart rate in restrictive CM (r = 0.95, P <.0001). The high S/D ratio found in restrictive CM, found also in dilated CM, suggests that this index is generic to heart failure rather than to a specific disease. The S/D ratio is easily measured using Doppler flow, enhancing echocardiographic assessment of D function in children.
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