Journal
TRANSFUSION CLINIQUE ET BIOLOGIQUE
Volume 13, Issue 5, Pages 290-297Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.tracli.2006.11.005
Keywords
transfusion; parasites; malaria; Chagas disease; leishmaniasis; innate immunity; adaptative immunity; blood safety; adverse effects
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Besides bacteriae and viruses, parasite infections can be transmitted by blood as a consequence of blood transfusion. To be transmitted by blood transfusion, parasites must: -i) circulate in the blood stream of donors, -ii) comprise of certain physical characteristics and resist processing steps leading to the preparation of labile blood products (packed red blood cells, therapeutic frozen plasma, or platelet concentrates), -iii) survive conservation, further, to generate infection in the blood receiver, such parasites must retain infectivity. In this Forum, the main characteristics of parasites-with respect to transmissibility by blood exposure-are recalled. This forum will further discuss each of these topics and try to make an issue with possible risks in transfusion, in countries that are either non-endemic for the given parasite or which can afford implementation of preventive measures. (c) 2007 Elsevier Masson SAS. All rights reserved.
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