Journal
GUT
Volume 55, Issue 11, Pages 1650-1660Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/gut.2006.091454
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Funding
- Medical Research Council [G106/1138] Funding Source: researchfish
- MRC [G106/1138] Funding Source: UKRI
- Medical Research Council [G106/1138] Funding Source: Medline
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The diagnosis of fibrosis within liver disease is important for prognosis, stratification for treatment, and monitoring of treatment efficacy. The rising incidence and prevalence of nonalcoholic fatty liver disease ( NAFLD) has driven the search for accurate non-invasive tools of liver fibrosis within this condition. With the aid of a systematic review, we explore how the field has evolved from the discovery of simple blood parameters to panel markers of liver fibrosis. We will discuss the biological plausibility, limitations, potential uses, and emerging diagnostic techniques of non-invasive markers in this rapidly expanding field.
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