Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 56, Issue 5, Pages 1135-1139Publisher
WILEY-BLACKWELL
DOI: 10.1002/mrm.21046
Keywords
conjugate gradient; diffusion MRI; motion correction; 2D navigator
Funding
- EPSRC [EP/C53820X/1] Funding Source: UKRI
- MRC [MC_U120081323, MC_U120061309] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/C53820X/1] Funding Source: researchfish
- Medical Research Council [MC_U120081323, MC_U120061309] Funding Source: researchfish
- Medical Research Council [MC_U120061309, MC_U120081323] Funding Source: Medline
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Cardiac pulsatility causes a nonrigid motion of the brain. In multi-shot diffusion imaging this leads to spatially varying phase changes that must be corrected. A conjugate gradient based reconstruction is presented that includes phase changes measured using two-dimensional navigator echoes, coil sensitivity information, navigator-determined weightings, and data from multiple coils and averages. A multi-shot echo planar sequence was used to image brain regions where pulsatile motion is not uniform. Reduced susceptibility artifacts were observed compared to a clinical single-shot sequence. In a higher slice, fiber directions derived from singleshot data show distortions from anatomical scans by as much as 7 mm compared to less than 2 mm for our multi-shot reconstructions. The reduced distortions imply that phase encoding can be applied in the shorter left-right direction, enabling time savings through the use of a rectangular field of view. Higher resolution diffusion imaging in the spine permits visualization of a nerve root.
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