Journal
EVOLUTION
Volume 60, Issue 11, Pages 2399-2402Publisher
WILEY
DOI: 10.1111/j.0014-3820.2006.tb01874.x
Keywords
analysis of molecular variance; F-ST; genetic variation; microsatellites; mutation rate; population structure
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Comparison of population structure between studies can be difficult, because the value of the often-used F-ST-statistic depends on the amount of genetic variation within populations. Recently, a standardized measure of genetic differentiation was developed based on G(ST), which addressed this problem, though no method was provided to estimate this standardized measure without bias. Here I present a method to estimate a standardized measure of population differentiation based on the analysis of molecular variance framework. One advantage of the method is that it can be readily expanded to include different hierarchical levels in the tested population structure.
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