4.3 Article

Factor VIII and thrombin generation assays: relevance to pharmacokinetic studies in haemophilia A

Journal

HAEMOPHILIA
Volume 12, Issue -, Pages 23-29

Publisher

BLACKWELL PUBLISHING
DOI: 10.1111/j.1365-2516.2006.01330.x

Keywords

FVIII assays; thrombin generation

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This article reviews the problems associated with traditional Factor VIII (FVIII) assays in pharmacokinetic studies, and the advantages, disadvantages, and technical aspects of thrombin generation assays as a replacement or additional tool.

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