4.3 Review

Recurrent glioblastoma multiforme: advances in treatment and promising drug candidates

Journal

EXPERT REVIEW OF ANTICANCER THERAPY
Volume 6, Issue 11, Pages 1593-1607

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1586/14737140.6.11.1593

Keywords

chemotherapy; gene therapy; glioblastoma multiforme; immunotherapy; recurrence; small molecule cell cycle inhibitors

Categories

Funding

  1. NCI NIH HHS [R21CA 103276, P50 CA 108961] Funding Source: Medline

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Recurrent giloblastoma multiforme, is a lethal disease with currently available treatment options having a limited impact on outcome. In this article, current and novel therapeutic approaches in the treatment of recurrent glioblastoma multiforme, including chemotherapy, targeted molecular agents, virotherapy/gene therapy and immunotherapy and challenges in developing novel therapeutic agents for glioblastoma multiforme will be discussed.

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