Journal
GENESIS
Volume 44, Issue 11, Pages 565-572Publisher
WILEY-LISS
DOI: 10.1002/dvg.20249
Keywords
AVE; embryology; anterior; patterning; migration
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Funding
- Wellcome Trust Funding Source: Medline
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The Anterior Visceral Endoderm is an extra-embryonic tissue that plays a pivotal role during embryogenesis, being responsible for the proper orientation of the anterior-posterior axis of the embryo and for appropriate pattering of adjacent embryonic tissue. In this review I discuss the formation and migration of the AVE, and attempt to place some recent findings in the context of a working model.
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