Journal
SOUTH AFRICAN JOURNAL OF BOTANY
Volume 72, Issue 4, Pages 555-558Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.sajb.2006.03.014
Keywords
6-hydroxydihydrochelerythrine; 6-methoxy-7-demethyldihydrochelerythrine; benzo[c]phenanthridine alkaloids; Rutaceae; Zanthoxylum davyi
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The stem bark of the southern African ethnomedicinal tree Zanthoxylum davyi (Rutaceae) has yielded five benzo[c]phenanthridine alkaloids, chelerythrine, dihydrochelerythrine, bocconoline, 6-hydroxydihydrochelerythrine and 6-methoxy-7-demethyldihydrochelerythrine, togetherwith 4-methoxy-1-methyl-2(1H)-quinolinone and the uncommon lignan meso-sesamin. The chemotaxonomic and ethnopharmacological relevance of these compounds is discussed, particularly that of the well-documented antimicrobial and anti-inflammatory chelerythrine. (c) 2006 SAAB. Published by Elsevier B.V. All rights reserved.
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